I rely on the feeling, the sounds, the words on the sign, or by analogy to another thing. I don't remember what it looked like in the way that in a dream I believe I physically see things
Maybe you disagree, but I don't think infliximab or even rituximab is close to the same level of importance as things like penicillin, Thorazine, misoprostol, or oral rehydration therapy. Insulin is, and it's technically a biological, but it was pre-01962.
I listed the three antivirals I think were revolutionary rather than evolutionary (all of which were post-01962), and I did list lovastatin, which was the first statin available, and widely applicable, and therefore the revolutionary one.
Sorry about my eyes glazing over - I think you are badly underselling how important the biologicals have been in recent decades, and also how there are both revolutionary but won't be used for various reasons mostly around cost (e.g. cas9 therapies) or haven't seen the full impact for yet (car-t therapies, which are wiping out the liquid cancers that the other biologicals didn't get)
That is very relevant overall and I thank you for bringing it to my attention. But what I'm talking about are people who declare tariffs as an absolute bad and then go on to say enacting them is rational and good. In the beggar thy neighbor policy, the behavior is not considered an absolutely bad thing. This happens with tariffs as well, but people can be even more dogmatic about it.
Think of it like an invasion - shooting people is probably as close to an absolute bad thing as you can get, but if you're getting shot at its pretty much time to start shooting back
- Shooting someone is absolutely bad in all scenarios
- Its correct to shoot someone if they are trying to shoot you
I agree with the second point completely. The problem is if you say that, you should go back and revise the first point, because clearly its not absolutely bad.
In the case of tariffs, once you acknowledge that reciprocal tariffs are good, you run into a problem because the US generally has lower tariffs on other countries than other countries have on it.
It's worth while reading the literature on pre-insulin treatments, but for type 1 diabetics, the answer is: you might be able to live, if just, for a while (a decade or so), but lifespans are greatly shortened. Probably depends exactly on the particular characteristics of the disease for a patient.
If you sold alcohol called "Safe Drive Juice", implied in advertisement that you can drive safe while drinking it, even made you a better driver, in tweets and press releases said that this is the future and everyone should use it, and if they did they'd be safer drivers, it doesn't matter if you put a note at the bottom that said "doesn't actually let you drive safe, please don't drink and drive"
Yes, that's the part here - you die without factor VIII. Its why severe hemophiliacs almost always died before factor VIII because available, and why almost 100% of them had HIV and hepC in the window between those viruses entering the blood supply and 100% testing / heat treatment (which is darkly funny because one of the trials involved was about heat treatment, seems to work for HIV but not for hepC).
From what I can tell, the issue is twofold: Informed consent, of which there was very little, but that's not exactly rare until recently, and running the trials on "marginal cases" - hemophilia comes in differing severity, and given the risks of using known contaminated factor VIII using it unless necessary probably wasn't the best idea.
I'm so tired of (usually conservative) people who obviously have never even heard of the BLS try to talk about how "fake" the unemployment rate is.
No, actually, there are 7 different variations of that metric, and they are all extremely correlated with each other. The reality is that unemployment by all metrics is extremely low. Cry about it conservatives.
Not a conservative, quite the opposite in fact! I simply don't trust the government to report correctly on statistics that are levers for public sentiment. Interest rates, inflation, unemployment... All of those come with an incentive to misreport, to twist behavior.
Let's couple those unemployment statistics to income and see which jobs are growing. Hint, it won't be any good jobs. Which is the actual problem: too many jobs in America are "not meant for you to live on" and most economic opportunity is insufficient for significant economic improvement at the ground level of society.
