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Magazine and game covers had such cool art then. It's still a joy to look at them after so many years.

RIP Mr Tinney.


I know that all investments have risk, but this is one risky gamble.

US$700 billion could build a lot of infrastructure, housing, or manufacturing capacity.


There is no shortage of money to build housing. There is an abundance of regulatory burdens in places that are desirable to live in.

Its not due to a lack of money that housing in SF is extremely expensive.


SF is not the only place where housing is expensive. There are plenty of cities where they could build more housing and they don't because it isn't profitable or because they don't have the workers to build more, not because the government is telling them they can't.

It is expensive in those other places for similar reasons as SF -- the government either tells them they can't (through zoning), or makes it very expensive (through regulation, like IZ / "affordable" housing), or limit profitability (rent control), or some combination of the above. All of these reduce the supply of new housing.

Generally the cities where housing is expensive are exactly the ones where the government is telling people they can't build (or making it very expensive to get approval). Do you have a specific example of a city such as you claim?

Which cities, for example?

> US$700 billion could build a lot of infrastructure, housing, or manufacturing capacity.

I am now 100% convinced, that the US has power to build those things, but it will not, because it means lives of ordinary people will be elevated even more, this is not what brutal capitalism wants.

If it can make top 1% richer in 10 year span vs good for everyone in 20 years, it will go with former


What $700 billion can't do is cure cancers, Parkinsons, etc. We know because we've tried and that's barely a sliver of what it's cost so far, for middling results.

Whereas $700 billion in AI might actually do that.


Your name is well earned! "can't cure cancers" is impressively counterfactual [0] as 5 year survival of cancer diagnosis is up over almost all categories. Despite every cancer being a unique species trying to kill you, we're getting better and better at dealing with them.

[0]https://www.cancer.org/research/acs-research-news/people-are...


Treating cancer is not the same as curing it. Currently, no doctor would ever tell you you are "cured", just that you are in remission.

Cancer is approaching being a managed chronic disease. That isn’t remission.

In my experience, most people with cancer that I know simply oscillate between having life-threatening active cancer/tumors and remission.

I don't know any case where people have detectable cancer and it's just being managed, I think that's more the exception than the rule.

For my girlfriend, when she was in her last stages they had to do that (try to slow down/manage the cancer instead of remove it), but that was already palliative care and she died soon after. Also, the only reason they didn't try removing the tumor is because the specific location in the brain (pons) is inoperable.


Yes, we're getting better at treating cancers, but still if a person gets cancer, chances are good the thing they'll die of is cancer. Middling results.

Because we're not good at curing cancers, we're just good at making people survive better for longer until the cancer gets them. 5 year survival is a lousy metric but it's the best we can manage and measure.

I'm perfectly happy investing roughly 98% of my savings into the thing that has a solid shot at curing cancers, autoimmune and neurodegenerative diseases. I don't understand why all billionaires aren't doing this.


How AI will cure neurodegenerative diseases and cancer?


If we knew that we probably wouldn’t need AI to tell us.

But realistically: perhaps by noticing patterns we’ve failed to notice and by generating likely molecules or pathways to treatment that we hadn’t explored.

We don’t really know what causes most diseases anyway. Why does the Shingles vaccine seem to defend against dementia? Why does picking your nose a lot seem to increase risk of Alzheimer’s?

That’s the point of building something smarter than us: it can get to places we can’t get on our own, at least much faster than we could without it.


I don’t think that lack of intelligence is the bottleneck. It might be in some places, but categorically, across the board, our bottlenecks are much more pragmatic and mundane.

Consider another devastating disease: tuberculosis. It’s largely eradicated in the 1st world but is still a major cause of death basically everywhere else. We know how to treat it, lack of knowledge isn’t the bottleneck. I’d say effectively we do not have a cure for TB because we have not made that cure accessible to enough humans.


That’s a weird way to frame it. It’s like saying we don’t know how to fly because everyone doesn’t own a personal plane.

We have treatments (cures) for TB: antibiotics. Even XDR-TB.

What we don’t have is a cure for most types of cancer.


Flying is a bad example because airlines are a thing and make flying relatively accessible.

I get your point, but I don’t think it really matters. If a cure for most (or all) cancers is known but it’s not accessible to most people then it is effectively nonexistent. E.g it will be like TB.

> We have treatments (cures) for TB

TB is still one of the top 10 causes of death globally.


Things like antibiotics are plenty accessible - 3rd world countries are literally overusing and misusing antibiotics to the point of causing drug resistance in TB. "Effectively we do not have [thing] because we have not made that [thing] accessible to enough humans" is an exercise in goal-post moving.

About 15% of people over the age of 15 are illiterate, but it'd be silly to say "effectively we don't have literacy", even in a global context. Depending on the stat, 1 in 10 don't have access to electricity, but electricity has been in 50% of American homes for over 100 years.

The reality is that the future is unevenly distributed. AI and more broadly technology as a whole, will only exacerbate that uneven distribution. That's just the reality of progress: we didn't stall electrifying homes in NYC because they didn't get electricity in Papua New Guinea.

If AI discovers a cure for cancer, it may be incredibly unevenly distributed. Imagine it's some amp'd-up form of CAR-T, requiring huge resources and expenses, but offering an actual cure for that individual. It'd be absurd to say we couldn't consider cancer cured just because the approach doesn't scale to a $1 pill.


> As an example, in the UK in 2013 the cost of standard TB treatment was estimated at £5,000 while the cost of treating MDR-TB was estimated to be more than 10 times greater, ranging from £50,000 to £70,000 per case.

I pulled this from Wikipedia. It does not look like TB treatment is “plenty affordable”.

If the issue is with the semantics of the word “cure” that’s not a hill I’ll die on, but can you see how knowing how to cure something and actually curing something are two vastly different things?


So let’s flip things: how widespread or how cheap does something have to be for you to consider it to exist? Everyone on earth, available for $1?

To say something is “effectively nonexistent” because it’s not got literal 100% availability for the world’s populace is just weird.


If you told someone a cure for cancer existed but there’s literally no way they could afford it, that sounds a lot like the cure effectively doesn’t exist for that person.

So I’ll posit that the weirdness of such a statement depends entirely on your audience.

If you’re one of the people likely to be able to afford such a cure, it might sound nonsensical.

I’ll also note that I intentionally selected a term with a more narrow definition “effective existence” vs a more general term “existence”. E.g. something can be true in general but effectively false in practice.


Maybe it should give you pause then, that not everyone else is investing 98% of their savings?

It gives me pause that most people drive cars or are willing to sit in one for more than 20 minutes a week.

But people accept the status quo and are afraid to take a moment’s look into the face of their own impending injury, senescence and death: that’s how our brains are wired to survive and it used to make sense evolutionarily until about 5 minutes ago.


Ah, yes: "well, we can't cure cancer or autoimmune and neurodegenerative diseases, but I'm willing to invest basically all my money into a thing that's...trained on the things we know how to do already, and isn't actually very good at doing any of them."

...Meanwhile, we are developing techniques to yes, cure some kinds of cancer, as in every time they check back it's completely gone, without harming healthy tissue.

We are developing "anti-vaccines" for autoimmune diseases, that can teach our bodies to stop attacking themselves.

We are learning where some of the origins of the neurodegenerative diseases are, in ways that makes treating them much more feasible.

So you're 100% wrong about the things we can't do, and your confidence in what "AI" can do is ludicrously unfounded.


Every doctor and researcher in the world is trained on things we already know how to do already.

I’m not claiming we haven’t made a dent. I’m claiming I’m in roughly as much danger from these things right now as any human ever has been: middling results.

If we can speed up the cures by even 1%, that’s cumulatively billions of hours of human life saved by the time we’re done.


But what they can do, that AI can't, is try new things in measured, effective, and ethical ways.

And that hypothetical "billions of hours of human life saved" has to be measured against the actual damage being done right now.

Real damage to economy, environment, politics, social cohesion, and people's lives now

vs

Maybe, someday, we improve the speed of finding cures for diseases? In an unknown way, at an unknown time, for an unknown cost, and by an unknown amount.

Who knows, maybe they'll give everyone a pony while they're at it! It seems just as likely as what you're proposing.


> I don't understand why all billionaires aren't doing this.

I know, shocking isn’t it?


In the 1980's TV ads in Uruguay were really simple. Some were just a static bi-colour image of a shoe or a coat, some text, and a voice would say "buy shoes at such shop at such address".

I guess that was at the same time the low point of marketing and also its most honest stage.


I have a P166 under my desk and once in a blue moon I try to run something on it.

My biggest obstacles are that it doesn't have an ethernet port and that it doesn't have BIOS USB support (although it does have a card with two USB ports).

I've managed to run some small Linux distros on it (I'll definitely try this one), but, you're right, I haven't really found anything useful to run on it.


Could you share motherboard vendor and model I will check your options

I have P1 90mhz P2 500mhz and typing from P4 just now :P

I think biggest limit will be missing SSE2 PAE POPCNT modern distros need this


EVs have breaks, suspensions, and tires like all cars. A responsible owner should have his car checked out once a year.


That's just magical thinking.

And Ethiopia couldn't get US$5 billion loan for a dam to service 60 million people.

The world is sick.


Out of curiosity, what personal blight have you faced to better the world?


Just last week I was tasked with configuring an automated happy birthday email.

It feels worse to know that it's just an automatic message and that the person who supposedly signed it doesn't even know who you are.

Work is just work, don't expect anything more than that.


This wouldn't be legal in my country unless all the apartments had one owner, because the telcos have a monopoly on communications.

The law says one person can't stretch a cable over to his neighbour, because they would need a licence for that (although if you did do that, who would know?).


My parents shared coaxiale television for years with the neighbors. Technically illegal but there is no way to know with analogue television.


I think our phone lines must work differently, the entire infrastructure is owned by one company (BT) who must lease it to other companies. So they can do things like this, as everyone needs a router at the end to access it and that's how they charge per customer.

There is a separate cable network, again one operator (Virgin), who don't lease it out.


It's funny how close an early PC was to the 8-bit machines: you had BASIC in ROM and a cassette interface.

You could even use a TV!


I have made the mistake of calling the early PC 8-bit, lolol...

Yes, it reminds me of an Apple ][ computer, with the major difference being the Apple had the video sub-system on board, and the PC locating that on a card.

I often wonder how things might have played out had the Apple ][ computers used one slot for video... or, had IBM chose to do it the Apple way.

Apple computers all sort of gravitated to the onvoard video despite a few cards being made. It was just enough, especially when the later models included 80 column text.

I ran my first PC on a TV. Same as the Apple and Atari machines.

Fun times.


Cool. I remember getting one such disc in a music magazine in the 80s. It occured to me then that you could maybe put software on it, but I never saw this implemented.


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