"This furin-like cleavage site, is supposed to be cleaved during virus egress (Mille and Whittaker, 2014) for S-protein “priming” and may provide a gain-of-function to the 2019-nCoV for efficient spreading in the human population compared to other lineage b betacoronaviruses. This possibly illustrates a convergent evolution pathway between unrelated CoVs. "
Getting permission to do research on a schedule 1 drug is pretty tricky, from what I understand? Since marijuana is schedule 1 it's termed as having a) no medical benefit and b) a high potential for abuse, which puts you in something of a catch-22 situation: you can't justify the research on medical grounds because the drug has no medical benefit (or it wouldn't be sched 1), and you can't justify research for exploratory purposes because of the potential for abuse (or else it wouldn't be sched 1), and then it becomes hard to find research that says "Actually, weed has medical uses and isn't nearly as abusable as heroin" because no research can be conducted.
Edit: To clarify, that's not to say that marijuana _should_ be schedule 1, only that it _is_ schedule 1 and moving something out of sched 1 is challenging because the research position is tricky.
>> Since marijuana is schedule 1 it's termed as having a) no medical benefit
Eye. Roll. I always thought this was the most absolutely bullshit, patently false thing I'd seen in law for time.
The medical benefits of THC have been well-established for decades. The sheer idea that there were ever arrests related to this plant is a disgusting mark on how shitty humanity can be, and how unwilling it is to acknowledge when it is wrong.
I know people who are extremely dependent on weed, who will have anxiety attacks without it. It's less dangerous than most drugs, but there are people who are important to me that I wish could function without it. I'm talking grown adults, with families, who do nothing but play video games.
Their problems would exist without the weed, but it seems to play a part in their stagnation. I guess I just don't know that many people who will just occasionally smoke it, it seems to turn into a lifestyle as much as any other drug.
Honestly, I've met many daily smokers in my life. Heck, I've been one off and on and tend to like to do it most weekends. I greatly prefer it to alcohol.Most folks can quit quite easily: At most, a few weeks of decreased appetite and trouble falling asleep. The worst effects wear off in the first week. The few folks I've met that have trouble without it have mental health issues, such as anxiety attacks. The worst thing about that situation is that one has to be able to find decent medical care and risk getting anxiety attacks - which I've read are horribly scary - to feel comfortable giving up smoking. And even then they might find that the smoking helps the best with the fewest side effects...unfortunately.
Also, most adults I've met who smoke regularly do all the family stuff just fine. They work, they play with their kids (more happily when a little stoned!), and so on. I mean, sure, it makes you more happy with a slightly messier house and more happy just being, but the other thing with that lowered happiness thresh hold is being happier when going on walks or playing boring kids games. Sure, happier with a slightly messier house but also happier to do the cleaning. Happier to eat more healthily, and so on.
Not many people would believe that you can be a better parent after consuming cannabis. I'm a much better parent after consuming cannabis. I listen more, play harder and can let go of the parental thoughts that silently occupy my brain when I'm sober and playing with my kids. Cannabis really helps me let go of parental world and enter theirs for just a little while..
Not many folks admit it, but yours isn't the first story I've heard with this. I don't personally have children, and have merely played with other people's children. I can definitely play longer slightly stoned.
Most folks aren't getting overly stoned with their children around anyway: More similar to having some wine with dinner, I guess?
This is the kind of thing I always read, but have never seen. I don't doubt you, or Joe Rogan. I've just personally never seen an adult who takes just a couple puffs every once in awhile. In my experience, it is a lifestyle of playing video games and sitting around smoking, unless they are someone who also uses other drugs and/or drinks a lot.
It may be anecdotal, but that is the reason it concerns me. It doesn't appear to be a positive for the numerous people I've known.
You've not met that many folks that smoke then. You know the few folks that meet a stereotype. Lots of folks sit around playing video games while sober, btw, and you are basically complaining that they aren't doing something with their life you approve of.
But more seriously, if you were... say... managing a retail store or a lawyer or some other professional position - how many folks would you let know that you smoke occasionally? The more folks you tell, the more chances you have of losing your job. You might lose your house and your children and everything you've worked for.
I'm definitely not trying to blame weed, if people can use it responsibly I say great! The problem is people who have conditions like anxiety who become dependent on it to get by. Some people become alcoholics because they have stuff going on that they can't deal with, and that doesn't mean I think alcohol should be illegal. But just like them, I wish the drug wasn't a numbing agent that prevents them from dealing with the underlying problem.
I don't see an issue. I also don't see an issue with folks going to therapists, taking SSRI's or other medicines, and so on. So long as the weed isn't doing undue damage to their health, go for it. Psychiatric medications often come with their own health concerns, sometimes you get the concern and sometimes you don't. Unfortunately, many folks make a distinction between those prescriptions and weed, but rarely say a word if folks pour their anxieties into over-exercise. To me, none of it matters if it makes their life better, if it is worth the consequences, and it isn't harming others (within reason).
It isn't like alcohol where doing it daily will absolutely destroy your life (legal issues aside). It doesn't have the same destroying effects on the family, friends, and so on.
And to be fair, if there is an underlying problem, it doesn't really prevent folks from dealing with it either. Lots of folks go to therapy while smoking regularly. If it doesn't need therapy, then it probably takes care of the issue... since it keeps the anxiety attacks at bay.
Oh, don't get me started on that. Not just ADHD, but antidepressants and anxiety medication as well. Of course there are people with legitimate needs, and boys who truly can't pay attention, but the over-prescription of these medications is negatively effecting way too many people.
Not working on your issues, and just masking them with a chemical should be a short term solution. These drugs are worse in my opinion, and I could ramble for a long time on my reasons.
The money they cost and dr's never having an exit strategy for the patient, are my biggest concerns. I've never heard of a dr informing a patient on how difficult getting off these things are. Presumably because they want you to take it forever, or they have no clue. And there are definitely too many boys who just don't get the attention they need, or have more energy than someone likes, so their behavior becomes a disease.
I drink sometimes, and have been known to do other things. But I feel like everyone should be striving for the ability to get through life without 'needing' chemicals. Sometimes people forget how wonderful you can feel when you are clean, eating right, and exercising. They start to think they are incomplete without some chemical. Of course we all fail at being perfect, but it's a goal worth struggling towards.
> I mean, sure, it makes you more happy with a slightly messier house and more happy just being
From my experience, this feeling comes from SSRIs and not cannabis. The former uniformly masks my anxieties whereas the latter only takes away the inhibition of thinking critically about your actions and their consequences... I find cannabis is a crutch for meditation.
So which recreational drug would you say is safer than marijuana then and why? I could see making a case for psilocybin and psilocin. Is that what you're arguing? That the psilocybin and psilocin contained in magic mushrooms are safer than the THC and other cannabinoids contained in marijuana? I would agree with that. If not that, then which drug would you say is safer?
> Do you mind if I ask how old you are? The rights of women to freely choose careers, and to make their own reproductive decisions, are at least several decades old.
i think OP of this subthread means "new" in the context of human society "new". Several decades is still pretty "new" if you take into account human history.
> i think OP of this subthread means "new" in the context of human society "new". Several decades is still pretty "new" if you take into account human history.
The "woman stays at home taking care of the children and the man goes out and earns enough to feed the family" concept is also new if you take into account human history.
It got introduced for the most part during the 19th century. Before that you couldn't afford to not let the women work anyway. Actually, during the industrial revolution and the growing social disorder there, you also couldn't afford to not let women and children work but often you had to.
And if you look at the whole of human history, the most common model of raising children was by a whole community. From groups of 5-10 individuals to even larger communities, all were somewhat responsible for and watching the growing children.
The idea that everybody could raise a child with only two or even worse just one parent is laughable if it weren't so sad that it's a common view.
quite true, but I feel like the "mother at home" cultural artifact still feels older in modern (european/american) human's psyche. It wasn't the best system, but it feels like the system that most of our societal changes have been seeking to rectify.
Your point about the 19th century is also interesting as its (mother at home) origins in that time period may explain why it's so ingrained and also deemed the default. It arose during the time of the biggest jump in human technological advancement (industrial revolution). Most of the propaganda for it references this correlation and uses it as a justification.
I don't agree with this sort of connection, but it is interesting to note.
